Robotics Engineer for Automation of Ultrathin Brain Sectioning
The FlyWire Consortium, led by the Princeton Neuroscience Institute, recently released the first neuronal wiring diagram of an adult brain. The fruit fly connectome was obtained by processing electron microscopic brain images to reconstruct tens of millions of synapses between 100,000 neurons. With this historic milestone attained, neuroscience has clearly entered the connectomic era.
The image processing benefited from modern high performance computing and artificial intelligence. But the images were acquired from slices of the fly brain that were collected manually, in a manner that has remained essentially unchanged for over 50 years. We are building an engineering team to modernize the collection of ultrathin brain slices with a pick-and-place robot guided by computer vision. The task is to pick up slices floating on water and place them on substrates suitable for electron microscopic imaging. This is the kind of technological innovation necessary to scale up connectomics from flies to large mammalian brains more like our own.
We are seeking a robotics engineer to design and build the robot, interface it with a control system, and collaborate with a robot vision engineer to control the pick and place operations.
This full-time position has an initial appointment of one year and possibility of renewal based on satisfactory performance. For more information, see these publications.
Timothy J. Lee et al. Large-scale neuroanatomy using LASSO: loop-based automated serial sectioning operation. PLoS One 13:e0206172 (2018).
John Ngai. BRAIN 2.0: Transforming neuroscience. Cell 185, 4-8 (2022).
Sven Dorkenwald et al. Neuronal wiring diagram of an adult brain. bioRxiv 2023.
Key Responsibilities :
Essential Qualifications:
Preferred Qualifications:
Princeton University is an Equal Opportunity/Affirmative Action Employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability status, protected veteran status, or any other characteristic protected by law. KNOW YOUR RIGHTS
PI250544149
About Princeton University
Princeton University is a vibrant community of scholarship and learning that stands in the nation's service and in the service of all nations. Chartered in 1746, Princeton is the fourth-oldest college in the United States. Princeton is an independent, coeducational, nondenominational institution that provides undergraduate and graduate instruction in the humanities, social sciences, natural sciences and engineering.As a world-renowned research university, Princeton seeks to achieve the highest levels of distinction in the discovery and transmission of knowledge and understanding. At the same time, Princeton is distinctive among research universities in its commitment to undergraduate teaching.Today, more than 1,100 faculty members instruct approximately 5,200 undergraduate students and 2,600 graduate students. The University's generous financial aid program ensures that talented students from all economic backgrounds can afford a Princeton education.
Connections working at Princeton University...Job Title: Business Development Manager/Lead Technology Solutions Location:Anywhere in TX is fine Travel Requirement:... .... Position Overview: BuzzClan is seeking an experienced Sales Lead to drive the growth of our technology and staffing solutions...
...an innovative Aerospace and Defense company that is seeking a Warehouse Manager to oversee and optimize their warehouse operations in... ...aspects of warehouse operations, including receiving, storing, and shipping materials. Ensure the efficient handling of goods, adherence...
...Job Description Job Description Estamos Contratando URGENTE!! Muy buen trabajo de limpieza Tiempo Completo, Horas Estables, limpieza comercial en WEST LOS ANGELES, CA. Estamos buscando A 1 J anitor para unirse a nuestro equipo! Seria responsable de mantener...
...The Opportunity: Are you an experienced Travel Agent who is looking for their next challenge? Have you worked with Sabre in the past? Do you pride yourself on... ...sounds like you, Fisher Investments may be your next home. We're looking for a highly talented individual...
...or security tools Knowledge of AI/ML, particularly in production environments Understanding of modern security frameworks (MITRE ATT&CK) Experience with real-time data processing and streaming Prior experience as a technical founder or early employee...